Optimization of Bacitracin Production by Bacillus licheniformisB5
نویسندگان
چکیده
منابع مشابه
The production of bacitracin synthetase by Bacillus licheniformis ATCC 10716.
Bacitracin synthetase is an enzyme complex [ 1,2] composed of three complementary fractions called A, B and C [3] (see fig.1). F’hosphopantetheine which is covalently bound to the fractions [2,3,.5] is probably involved in the biosynthesis of bacitracin. Similar to gramicidin S and tyrocidine [6] its mechanism of synthesis has been described as a thiotemplate mechanism [7]. In the present work ...
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The present study is focused on the improvement of Bacillus licheniformis through random mutagenesis to obtain mutant having enhanced production of bacitracin. Many isolates of Bacillus licheniformis were isolated and the isolate GP-40 produced maximum bacitracin production (16±0.72 IU/mL). Treatment of Bacillus licheniformis GP-40 with ultraviolet (UV) radiations increased bacitracin productio...
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ژورنال
عنوان ژورنال: Pakistan Journal of Biological Sciences
سال: 2007
ISSN: 1028-8880
DOI: 10.3923/pjbs.2007.972.976